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Spring 2014 - “Introduction to Drug Discovery Research”

ME:200.704
"Introduction to Drug Discovery Research"

Course Director: Takashi Tsukamoto (ttsukamoto@jhmi.edu)
Location: Rangos Building Room 590
Time: 10:00 AM – 11:30 AM
Dates: Every Wednesday 1/8/2014 - 4/23/2014 (except for 3/12/2014)

This course deals with various aspects of the drug discovery process including target identification, medicinal chemistry, in vitro and in vivo drug screening methods, pharmacokinetics, drug safety, and intellectual property management. The last three lectures are devoted to case studies in which discovery of particular drugs will be discussed in detail to provide further insights into the process of drug discovery research. Each lecture is given by an expert on that respective subject with many years of drug discovery experience. The course is designed for students planning a career in pharmaceutical research or basic science with implications for drug discovery opportunities. Students will build a broad knowledge base that will allow them to effectively develop their skills in a particular area of drug discovery research for their future endeavors.

 
Topic   Lecturer
1/08 Introduction   Takashi Tsukamoto
1/15 Drug-like properties and druggable targets Takashi Tsukamoto
1/22 in vitro Pharmacology I Camilo Rojas
1/29 in vitro Pharmacology II Camilo Rojas
2/05 in vitro Pharmacokinetics Takashi Tsukamoto
2/12 in vivo Pharmacokinetics   Takashi Tsukamoto
2/19 Drug Safety  Adaline Smith
2/26 Midterm Exam  
3/05 in vivo Pharmacology Krystyna Wozniak
3/19 Intellectual Property Jeff Childers
3/26 Lead Optimization  Takashi Tsukamoto
4/02 Case Study I David Meyers
4/09 Case Study II Dana Ferraris
4/16 Case Study III   Jim Barrow
4/23 Final Exam  

Grades will be determined by:

Quiz participation (given at the end of each lecture, 1/3) No quiz will be given at the first lecture.

Mid-term Exam (1/3)

Final Exam (1/3)

Prerequisite: No prior knowledge in drug discovery is required. This course is recommended for students in the 2ndor later year of their graduate program.

Please contact Dr. Takashi Tsukamoto (ttsukamoto@jhmi.edu) for more information. 

 
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