research: Research Areas
The BSi supports many different aspects of brain research throughout Johns Hopkins University. We look for innovative and collabortive efforts that will propel the disciplines further and can lead to translation of discoveries to treatments of brain diseases. Here is a list of our current and previous research interests.

Synapses, Circuits and Cognitive Disorders
Research in this area addresses the fundamental role of synapses in brain function as well as addresses the mechanisms underlying cognitive disorders such as Alzheimer’s disease, schizophrenia and autism.

Regeneration and Repair in the Nervous System

This research focuses on the functional and structural repair of the damaged nervous system. Interdisciplinary teams are studying how neurons recover and regenerate from inquiry and trauma. These studies may have significant impact on therapeutic treatment of brain traumas from stroke and spinal injury as well as veterans suffering from physical trauma returning from war.

Schizophrenia

Research in this area addresses the processes underlying this devastating disease. Recent advances in molecular techniques have allowed genetic approaches towards this complex disorder. Collaborative studies in the forefront of this field are trying to identify the genes involved in schizophrenia and how disruption of these normal biological processes leads to illness.

Neurogenetics

The goal is to understand how genes are involved in brain function in health and disease. Researchers are studying genes in mice and humans to discover how mutations in genes can affect normal brain function and contribute to disease.

Perception and Cognition

Research in this area includes novel approaches to understand how we perceive and think. New collaborative efforts to investigate brain structure and function as well as study how we recognize patterns and how neuroscience can inform education.

Tramatic Brain Injury (TBI)

Traumatic brain injury (TBI), including that induced by mild, repetitive, non-penetrating injuries (eg, sports-related concussion) represents an enormous public health problem that is inadequately understood, has uncertain predictors, and is not addressed by existing therapeutics. Improving this situation will require a better understanding of the circumstances and underlying mechanisms by which brain injuries, even when relatively minor, lead to progressive neurodegeneration.

Pain

Research of the mechanisms underlying acute and chronic pain. Pathological pain represents an enormous public health problem that is inadequately addressed by the current therapeutic arsenal. Improving this situation will require a better understanding of the mechanisms by which the peripheral and central nervous   systems process noxious stimuli and by which the interpretation of these stimuli changes following inflammatory or neuropathic insults.