The following highlights the capabilities of the BSi NeuroTranslational Drug Discovery Program staff:
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Design, synthesis, purification, and characterization of small molecule drug candidates
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Hit identification, hit-to-lead selection and lead optimization
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High throughput screening assay development
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Receptor pharmacology
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Enzyme kinetics and mechanisms
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Primary cell culture and establishment of cell lines
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Preclinical toxicology
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Drug metabolism and pharmacokinetics
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Investigational New Drug (IND) enabling preclinical studies
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FDA regulatory filing
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Intellectual property creation